Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11624564 | 0.88 | ALOX15 (0.41) | GPR84ALOX15ALDH1A1MAPT | |
| SCHEMBL2123501 | 0.84 | PPARA (0.50) | CYP1A2CYP2C9CYP2C19KMT2ACNR1 | |
| SCHEMBL11123121 | 0.81 | ALOX15 (0.43) | CYP1A2CYP2C9CYP2C19ALOX15ALDH1A1 | |
| SCHEMBL18095847 | 0.81 | HRH4 (0.43) | SOAT1 | |
| SCHEMBL28940885 | 0.80 | RXRA (0.50) | CYP2C19MAPK1ALDH1A1MAPT | |
| SCHEMBL11679230 | 0.79 | CCNB2 (0.44) | MEN1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL2123894 | 0.79 | CYP3A4 (0.48) | CYP1A2CYP2C9CYP2C19KMT2ACNR1 | |
| SCHEMBL6089012 | 0.79 | CYP1A2 (0.46) | LIPGCYP1A2CYP2C9CYP2C19CDK1 | |
| SCHEMBL20449061 | 0.78 | TAAR1 (0.41) | CYP1A2ALOX15ALDH1A1MAPT | |
| SCHEMBL5326052 | 0.78 | TTK (0.48) | CYP2C9PLK4AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007517782-A | — | — | 2007-07-05 | — | — | JP | claimed |
| EP-1694123-A1 | TOPICAL FORMULATIONS COMPRISING A 1-N-ARYLPYRAZOLE DERIVATIVE AND A FORMAMIDINE | Merial Ltd. (US) | 2006-08-30 | — | — | EP | claimed |
| WO-2005058038-A1 | TOPICAL FORMULATIONS COMPRISING A 1-N-ARYLPYRAZOLE DERIVATIVE AND A FORMAMIDINE | MERIAL LIMITED (US) | 2005-06-30 | — | — | WO | claimed |