Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.52 |
| ▸ | HTR2C | P28335 | 6/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5143421 | 0.89 | SLC6A2 (0.46) | HTR2AHTR2CSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL3374322 | 0.86 | SLC6A2 (0.46) | HTR2AHTR2CSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL5145418 | 0.76 | CNR1 (0.48) | SLC6A2SLC6A4TP53 | |
| SCHEMBL598834 | 0.75 | HTR2A (0.54) | HTR2AHTR2CSLC6A2SLC6A4TP53 | |
| SCHEMBL5143423 | 0.74 | SLC6A2 (0.45) | HTR2AHTR2CSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL3376002 | 0.74 | PKM (0.42) | HTR2AHTR2CSLC6A2SLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL27666400 | 0.72 | SLC6A2 (0.53) | SLC6A2SLC6A3SLC6A4PNMTLMNA | |
| SCHEMBL6331322 | 0.71 | SLC6A2 (0.45) | HTR2AHTR2CSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL20876087 | 0.70 | SLC6A2 (0.50) | HTR2AHTR2CSLC6A2SLC6A4TP53 | |
| SCHEMBL20876045 | 0.70 | HTR2A (0.49) | HTR2AHTR2CSLC6A2SLC6A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070105914-A1 | Substituted sulfonamides | MERCK SHARP & DOHME CORP. | 2007-05-10 | — | — | US | disclosed |
| CN-1956949-A | Substituted sulfonamides | MERCK & CO INC (US) | 2007-05-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105914-A1 | Substituted sulfonamides | CNR2, CNR1, FAAH | HTR2A 481/4885HTR2C 378/4885SLC6A2 906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.