Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3375008 | 0.90 | CYP2D6 (0.52) | SLC6A2SLC6A3SLC6A4CYP2D6CYP3A4 | |
| SCHEMBL13113800 | 0.84 | CNR1 (0.52) | SLC6A2SLC6A3SLC6A4CYP2D6PNMT | |
| Hydrochloric Acid SCHEMBL3373474 | 0.83 | CNR1 (0.51) | SLC6A2SLC6A3SLC6A4CYP2D6LMNA | |
| SCHEMBL8627145 | 0.82 | ACP3 (0.54) | SLC6A2SLC6A3SLC6A4CYP2D6CYP1A2 | |
| SCHEMBL3374924 | 0.80 | SLC6A2 (0.56) | SLC6A2SLC6A3SLC6A4CYP2D6CYP1A2 | |
| SCHEMBL27614823 | 0.80 | SLC6A2 (0.56) | SLC6A2SLC6A3SLC6A4CYP2D6CYP1A2 | |
| SCHEMBL3374922 | 0.80 | SLC6A2 (0.56) | SLC6A2SLC6A3SLC6A4CYP2D6CYP1A2 | |
| Hydrochloric Acid SCHEMBL3371830 | 0.79 | SLC6A2 (0.55) | SLC6A2SLC6A3SLC6A4CYP2D6CYP1A2 | |
| Hydrochloric Acid SCHEMBL3371068 | 0.79 | SLC6A2 (0.55) | SLC6A2SLC6A3SLC6A4CYP2D6CYP1A2 | |
| SCHEMBL4691720 | 0.78 | SLC6A3 (0.62) | SLC6A2SLC6A3SLC6A4CYP2D6PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070105914-A1 | Substituted sulfonamides | MERCK SHARP & DOHME CORP. | 2007-05-10 | — | — | US | disclosed |
| CN-1956949-A | Substituted sulfonamides | MERCK & CO INC (US) | 2007-05-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105914-A1 | Substituted sulfonamides | CNR2, CNR1, FAAH | SLC6A2 906/4885SLC6A3 1482/4885SLC6A4 1052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.