Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.55 |
| ▸ | PPARA | Q07869 | 11/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5584846 | 0.92 | SLC6A2 (0.56) | PPARGPPARASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL5585131 | 0.85 | SLC6A2 (0.51) | PPARGPPARASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL3520897 | 0.76 | SLC6A2 (0.60) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL18763048 | 0.75 | PPARA (0.47) | PPARGPPARASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL8619498 | 0.74 | SLC6A2 (0.53) | PPARGPPARASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL5584927 | 0.73 | SLC6A2 (0.49) | PPARGPPARASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL5177950 | 0.73 | CNR1 (0.48) | PPARGPPARA | |
| SCHEMBL3518543 | 0.73 | SLC6A2 (0.56) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL3520850 | 0.71 | SLC6A2 (0.53) | PPARGPPARASLC6A2SLC6A3SLC6A4 | |
| Isopropylamine SCHEMBL17674511 | 0.71 | ADRB2 (0.54) | SLC6A2SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070105914-A1 | Substituted sulfonamides | MERCK SHARP & DOHME CORP. | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105914-A1 | Substituted sulfonamides | CNR2, CNR1, FAAH | PPARG 395/4885PPARA 711/4885SLC6A2 906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.