Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2307204 | 0.82 | TSHR (0.39) | TSHRALDH1A1THRB | |
| SCHEMBL5009659 | 0.81 | TSHR (0.38) | TSHRALDH1A1THRB | |
| SCHEMBL136942 | 0.79 | ALDH1A1 (0.40) | TSHRALDH1A1THRB | |
| SCHEMBL29022837 | 0.79 | TSHR (0.41) | TSHRALDH1A1THRB | |
| SCHEMBL1358594 | 0.78 | ALDH1A1 (0.39) | TSHRALDH1A1THRB | |
| SCHEMBL139124 | 0.78 | THRB (0.38) | TSHRALDH1A1THRB | |
| SCHEMBL9859593 | 0.78 | TSHR (0.37) | TSHRALDH1A1THRB | |
| SCHEMBL143269 | 0.77 | TSHR (0.39) | TSHRALDH1A1THRB | |
| SCHEMBL10782112 | 0.77 | TSHR (0.35) | TSHRALDH1A1THRB | |
| SCHEMBL28627711 | 0.77 | THRB (0.37) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241009-B2 | Crosslinking of silicones presence of functionalized silicones | CALHOUN VISION, INC. (US) | 2007-07-10 | — | — | US | disclosed |
| EP-1781212-A2 | CROSSLINKING OF SILICONES | Calhoun Vision, Inc. (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006002201-A2 | CROSSLINKING OF SILICONES | CALHOUN VISION, INC. (US) | 2006-01-05 | — | — | WO | disclosed |
| US-20050018310-A1 | Crosslinking of silicones presence of functionalized silicones | RXSIGHT, INC. | 2005-01-27 | — | — | US | disclosed |