Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14384248 | 0.72 | PPARD (0.60) | PPARD | |
| SCHEMBL5585973 | 0.71 | NOTUM (0.43) | MAPTNPC1RAB9ASMN1; SMN2NISCH | |
| SCHEMBL4608185 | 0.71 | SCN5A (0.40) | MAPTNPC1RAB9ASMN1; SMN2NISCH | |
| SCHEMBL27217117 | 0.69 | NR4A2 (0.41) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL2219797 | 0.68 | HRH3 (0.45) | MAPTNPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL5524819 | 0.67 | PTGS2 (0.35) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL5726725 | 0.66 | LPL (0.50) | ALDH1A1KDM4ENISCHPOLBCTDSP1 | |
| SCHEMBL4802707 | 0.65 | LPL (0.54) | MAPTNPC1RAB9AHSD17B10NISCH | |
| SCHEMBL21887379 | 0.65 | NISCH (0.47) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL10655296 | 0.65 | TDP1 (0.48) | MAPTNPC1RAB9AHSD17B10NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070244130-A1 | Compounds and Compositions as Ppar Modulators | IRM LLC (BM) | 2007-10-18 | — | — | US | disclosed |
| US-20070244130-A1 | Compounds and Compositions as Ppar Modulators | IRM LLC (BM) | 2007-10-18 | — | — | US | disclosed |
| US-20070244130-A1 | Compounds and Compositions as Ppar Modulators | IRM LLC (BM) | 2007-10-18 | — | — | US | disclosed |
| EP-1749003-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005116016-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2005-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244130-A1 | Compounds and Compositions as Ppar Modulators | PPARG, PPARA, PPARD | MAPT 3464/4885NPC1 425/4885RAB9A 2891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.