Demannose

Demannose

SCHEMBL5586151

CCCC(=O)O.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.45
HDAC3 O15379 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
PDE4A P27815 1/20 0.41
LMNA P02545 2/20 0.39
USP2 O75604 1/20 0.39
SLCO1B1 Q9Y6L6 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
FPR2 P25090 2/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
AKR1B1 P15121 2/20 0.34
KDM4E B2RXH2 2/20 0.33
FFAR4 Q5NUL3 1/20 0.33
FFAR1 O14842 1/20 0.33
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Demannose SCHEMBL27660938 1.00 FFAR3 (0.45) FFAR3HDAC3HDAC1HDAC2HDAC8
Demannose SCHEMBL28531529 0.98 FFAR3 (0.43) FFAR3HDAC3HDAC1HDAC2HDAC8
Xylose SCHEMBL18141104 0.95 FFAR3 (0.46) FFAR3HDAC3HDAC1HDAC2HDAC8
Xylose SCHEMBL16011524 0.95 FFAR3 (0.46) FFAR3HDAC3HDAC1HDAC2HDAC8
Xylose SCHEMBL20581742 0.95 FFAR3 (0.46) FFAR3HDAC3HDAC1HDAC2HDAC8
Demannose SCHEMBL30163433 0.90 FPR2 (0.44) PDE4AFPR2NFKB1NFKB2RELA
Demannose SCHEMBL18141631 0.90 FPR2 (0.44) PDE4AFPR2NFKB1NFKB2RELA
Demannose SCHEMBL28742780 0.90 FPR2 (0.44) PDE4AFPR2NFKB1NFKB2RELA
Demannose SCHEMBL4444321 0.89 PDE4A (0.47) PDE4ALMNAUSP2SLCO1B1L3MBTL1
Demannose SCHEMBL31490918 0.89 PDE4A (0.47) PDE4ALMNAUSP2SLCO1B1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102423114-B Low-tar cigarette aroma compensation method HONGTA TOBACCO GROUP CO LTD 2014-02-12 CN claimed
CN-102423114-A Low-tar cigarette fragrance compensation method HONGTA TOBACCO GROUP CO LTD 2012-04-25 CN claimed
CN-102423117-A Method for improving suction quality of paper-making sheet HONGTA TOBACCO GROUP CO LTD 2012-04-25 CN claimed
US-10428194-B2 Modified acrylic resin cured product, and laminate thereof, and production methods therefor MITSUI CHEMICALS, INC. (JP) 2019-10-01 US disclosed
EP-3263635-B1 MODIFIED ACRYLIC RESIN CURED PRODUCT, AND LAMINATE THEREOF, AND PRODUCTION METHODS THEREFOR MITSUI CHEMICALS INC (JP) 2019-09-18 EP disclosed
US-20180163056-A1 HYDROPHILIC CURABLE COMPOSITIONS MITSUI CHEMICALS, INC. (JP) 2018-06-14 US disclosed
US-20180036995-A1 HYDROPHILIC MONOLAYER FILM WITH OPTICAL FUNCTIONALITY AND STACK OF THE SAME MITSUI CHEMICALS, INC. (JP) 2018-02-08 US disclosed
US-20180030230-A1 MODIFIED ACRYLIC RESIN CURED PRODUCT, AND LAMINATE THEREOF, AND PRODUCTION METHODS THEREFOR MITSUI CHEMICALS, INC. (JP) 2018-02-01 US disclosed
EP-3270192-A1 HYDROPHILIC SINGLE-LAYER FILM HAVING OPTICAL FUNCTIONALITY, AND LAMINATE THEREOF Mitsui Chemicals, Inc. (JP) 2018-01-17 EP disclosed
EP-3263635-A1 MODIFIED ACRYLIC RESIN CURED PRODUCT, AND LAMINATE THEREOF, AND PRODUCTION METHODS THEREFOR Mitsui Chemicals, Inc. (JP) 2018-01-03 EP disclosed
US-20170209345-A1 DENTAL PROSTHESIS MITSUI CHEMICALS, INC. (JP) 2017-07-27 US disclosed
CN-106659639-A Dental prosthesis 三井化学株式会社 2017-05-10 CN disclosed
EP-3081578-A1 COMPOSITION FOR HYDROPHILIC CURED PRODUCT Mitsui Chemicals, Inc. (JP) 2016-10-19 EP disclosed
CN-102423114-B Low-tar cigarette aroma compensation method HONGTA TOBACCO GROUP CO LTD 2014-02-12 CN disclosed
CN-102423114-A Low-tar cigarette fragrance compensation method HONGTA TOBACCO GROUP CO LTD 2012-04-25 CN disclosed
CN-102423117-A Method for improving suction quality of paper-making sheet HONGTA TOBACCO GROUP CO LTD 2012-04-25 CN disclosed
US-20070059708-A1 Gene screen UNIVERSITY OF SHEFFIELD (GB) 2007-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170209345-A1 DENTAL PROSTHESIS CAD, OR10J3, PSMA3 FFAR3 988/4885HDAC3 1626/4885HDAC1 1215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.