SCHEMBL5586153

SCHEMBL5586153

C=Cc1nc(N)cc(N)n1

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
NOS2 P35228 3/20 0.33
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
CYP3A4 P08684 1/20 0.31
BLM P54132 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1372770 0.84
SCHEMBL13818927 0.72 ALDH1A1 (0.38) MAPTTDP1NOS2NOS3NOS1
SCHEMBL4452401 0.72 MAPT (0.39) MAPTTDP1NOS2NOS3NOS1
SCHEMBL21306214 0.71
SCHEMBL139174 0.71 LMNA (0.36)
SCHEMBL12805217 0.70
SCHEMBL8502028 0.67
SCHEMBL24737339 0.67 LMNA (0.42) TDP1NOS2NOS3NOS1
SCHEMBL5672948 0.67 S1PR2 (0.30)
SCHEMBL96485 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108950645-B Aluminum and aluminum alloy anodic oxidation nickel-free sealing agent 上海铝通化学科技有限公司 2020-10-23 CN disclosed
EP-1757667-A2 Adhesive composition and process for adhesion using the adhesive composition Bridgestone Corporation (JP) 2007-02-28 EP disclosed