Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.44 |
| ▸ | SKP1 | P63208 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3619817 | 0.95 | TGFBR1 (0.52) | TGFBR1MEN1KMT2AGAAPDK2 | |
| SCHEMBL3613446 | 0.91 | TGFBR1 (0.49) | TGFBR1MEN1KMT2AGAAPDK2 | |
| SCHEMBL3622976 | 0.86 | TGFBR1 (0.50) | TGFBR1MEN1KMT2AGAAPDK2 | |
| SCHEMBL3616980 | 0.86 | TGFBR1 (0.50) | TGFBR1MEN1KMT2AGAAPDK2 | |
| SCHEMBL3621035 | 0.84 | BCL2 (0.52) | TGFBR1MEN1KMT2AGAABCL2 | |
| SCHEMBL3615524 | 0.83 | TGFBR1 (0.49) | TGFBR1MEN1KMT2AGAAPDK2 | |
| SCHEMBL3613583 | 0.83 | TGFBR1 (0.47) | TGFBR1MEN1KMT2AGAAPDK2 | |
| SCHEMBL3622518 | 0.82 | TGFBR1 (0.53) | TGFBR1MEN1KMT2AGAAPDK2 | |
| SCHEMBL3618644 | 0.78 | TGFBR1 (0.51) | TGFBR1MEN1KMT2APDK2PIK3CA | |
| SCHEMBL6744636 | 0.77 | HTR6 (0.66) | TGFBR1MEN1KMT2APDK2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7173035-B2 | Arylsulfonamide compounds | BIOVITRUM AB (SE) | 2007-02-06 | — | — | US | disclosed |