SCHEMBL5586347

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6899941	0.84	POLB (0.39)	MIFKMT2APOLBMGAMGAA
	SCHEMBL5586161	0.83	BRD4 (0.39)	MIFMAPTGAACYP1A2CYP2D6
	SCHEMBL28101934	0.80	ALDH1A1 (0.43)	KMT2AMEN1GLAMAPTPOLB
	SCHEMBL7872110	0.79	ALDH1A1 (0.42)	KMT2AMEN1GLAMAPTPOLB
	SCHEMBL17461578	0.79	ALDH1A1 (0.42)	KMT2AMEN1GLAMAPTPOLB
	SCHEMBL28329582	0.77	TDP1 (0.32)	KMT2AMEN1GLAMAPTPOLB
	SCHEMBL3257424	0.77	MEN1 (0.62)	KMT2AMEN1GLAMAPTPOLB
	SCHEMBL30114611	0.77	L3MBTL1 (0.35)	POLBCYP1A2L3MBTL1ALDH1A1LMNA
	SCHEMBL8157771	0.77	L3MBTL1 (0.35)	POLBCYP1A2L3MBTL1ALDH1A1LMNA
	SCHEMBL28511345	0.76	ALDH1A1 (0.39)	MIFKMT2AMEN1MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.