Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EBP | Q15125 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5587151 | 1.00 | SIGMAR1 (0.40) | SIGMAR1ESR2ESR1KDM4EGRIN2D | |
| SCHEMBL5587239 | 0.83 | GRIN2D (0.35) | SIGMAR1KDM4EGRIN2DGRIN3BGRIN1 | |
| SCHEMBL5587234 | 0.83 | GRIN2D (0.35) | SIGMAR1KDM4EGRIN2DGRIN3BGRIN1 | |
| SCHEMBL5587881 | 0.82 | MAPT (0.40) | KDM4EMEN1KMT2AALOX15TSHR | |
| SCHEMBL5587887 | 0.82 | MAPT (0.40) | KDM4EMEN1KMT2AALOX15TSHR | |
| SCHEMBL16077921 | 0.81 | SIGMAR1 (0.40) | SIGMAR1KDM4EGRIN2DGRIN3BGRIN1 | |
| SCHEMBL5587571 | 0.81 | SIGMAR1 (0.40) | SIGMAR1KDM4EGRIN2DGRIN3BGRIN1 | |
| SCHEMBL16077918 | 0.81 | GRIN2D (0.40) | SIGMAR1KDM4EGRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL1539025 | 0.81 | SIGMAR1 (0.44) | SIGMAR1ESR2ESR1KDM4EGRIN2D | |
| Hydrochloric Acid SCHEMBL3290040 | 0.81 | SIGMAR1 (0.44) | SIGMAR1ESR2ESR1KDM4EGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247687-B2 | Late transition metal catalysts for olefin polymerization and oligomerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-07-24 | — | — | US | disclosed |
| EP-1521758-B1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2006-05-24 | — | — | EP | disclosed |
| US-20060047094-A1 | Late transition metal catalysts for olefin polymerization and oligomerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060047094-A1 | Late transition metal catalysts for olefin polymerization and oligomerization | MLX, LOX, LMTK3 | SIGMAR1 1143/4885ESR2 2269/4885ESR1 1108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.