Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.30 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5586795 | 0.89 | TDP1 (0.40) | IMPDH2TDP1PIM1CYP3A4MAPT | |
| SCHEMBL20256643 | 0.85 | TDP1 (0.39) | IMPDH2TDP1PIM1CYP3A4MAPT | |
| SCHEMBL5516691 | 0.85 | TDP1 (0.39) | IMPDH2TDP1PIM1CYP3A4MAPT | |
| SCHEMBL18090614 | 0.82 | TDP1 (0.38) | IMPDH2TDP1PIM1CYP3A4MAPT | |
| SCHEMBL1635332 | 0.80 | IMPDH2 (0.37) | IMPDH2TDP1PIM1CYP3A4MAPT | |
| SCHEMBL1052797 | 0.79 | TDP1 (0.39) | IMPDH2TDP1PIM1CYP3A4MAPT | |
| SCHEMBL12143217 | 0.79 | TDP1 (0.46) | IMPDH2TDP1PIM1CYP3A4MAPT | |
| SCHEMBL21670978 | 0.78 | TDP1 (0.43) | TDP1PIM1CYP3A4MAPTPDE4A | |
| SCHEMBL14089301 | 0.78 | TDP1 (0.40) | IMPDH2TDP1PIM1CYP3A4MAPT | |
| SCHEMBL5589032 | 0.78 | TDP1 (0.40) | TDP1PIM1CYP3A4MAPTPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103797047-A | Epoxybenzyl-terminated poly(arylene ether)s, method for preparation thereof, and curable compositions comprising same | SABIC INNOVATIVE PLASTICS IP | 2014-05-14 | — | — | CN | disclosed |
| CN-103649225-A | Aromatic polycarbonate resin composition and articles molded therefrom | MITSUBISHI ENG PLASTICS CORP | 2014-03-19 | — | — | CN | disclosed |
| CN-102361910-B | Method for monitoring monomer concentration in interfacial polycarbonate manufacturing process | STYRON EUROPE GMBH | 2013-10-16 | — | — | CN | disclosed |
| CN-101885812-B | Functionalized poly(arylene ether) composition and method | SABIC INNOVATIVE PLASTICS IP | 2013-09-11 | — | — | CN | disclosed |
| CN-101842411-B | Process for preparing poly (arylene ether) | SABIC INNOVATIVE PLASTICS IP | 2013-04-17 | — | — | CN | disclosed |
| CN-101668789-B | Method of separating a poly (arylene ether) composition from a solvent, and poly (arylene ether) composition prepared thereby | SABIC INNOVATIVE PLASTICS IP | 2012-06-20 | — | — | CN | disclosed |
| CN-102361910-A | Method for monitoring monomer concentration in interfacial polycarbonate manufacturing process | DOW GLOBAL TECHNOLOGIES INC | 2012-02-22 | — | — | CN | disclosed |
| CN-102224184-A | Process for preparing linear polycarbonates with improved impact properties | STYRON EUROPE GMBH | 2011-10-19 | — | — | CN | disclosed |
| CN-102224183-A | Method for recycling amine catalyst in interfacial polycarbonate manufacturing process | STYRON EUROPE GMBH | 2011-10-19 | — | — | CN | disclosed |
| CN-101885812-A | Functionalized poly (arylene ether) composition and method | GEN ELECTRIC | 2010-11-17 | — | — | CN | disclosed |
| EP-1521758-B1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2006-05-24 | — | — | EP | disclosed |
| US-20060047094-A1 | Late transition metal catalysts for olefin polymerization and oligomerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-03-02 | — | — | US | disclosed |
| CN-1235973-C | Polyalkylenterephthalate compositions stabilized with phosphite esters | BAYER AG (DE) | 2006-01-11 | — | — | CN | disclosed |
| CN-1681879-A | Thermoplastic stabilized with polymeric phosphites | LANEKESCHES DEUTSCHER BMBH (DE) | 2005-10-12 | — | — | CN | disclosed |
| CN-1646603-A | Copolymer containing one or more amide segments | STICHTING DUTCH POLYMER INST (NL) | 2005-07-27 | — | — | CN | disclosed |
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| CN-1511878-A | Conductive thermoplastic resin composition | 狮王株式会社 | 2004-07-14 | — | — | CN | disclosed |
| CN-1471558-A | Polyalkylenterephthalate compositions stabilized with phosphite esters | — | 2004-01-28 | — | — | CN | disclosed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | disclosed |
| CN-86105798-A | BROMINATED HYDROXYAROMATIC COMPOUNDS | — | 1987-04-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060047094-A1 | Late transition metal catalysts for olefin polymerization and oligomerization | MLX, LOX, LMTK3 | IMPDH2 4570/4885TDP1 3761/4885PIM1 959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.