SCHEMBL5588017

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5590309	0.91	BID (0.43)	PTPN1PTPN11DAGLAPPARGPPARA
	SCHEMBL5588073	0.90	PPARA (0.49)	PTPN1DAGLAPPARGPPARABID
	SCHEMBL5588765	0.90	PTPN1 (0.49)	PTPN1PTPN11PTPN2PRKCILDHA
	SCHEMBL5588241	0.89	METAP2 (0.40)	PTPN1PTPN11PTPN2BCL2L1METAP2
	SCHEMBL5587468	0.89	BID (0.51)	PTPN1DAGLAPPARGPPARABID
	SCHEMBL5587006	0.89	BID (0.51)	PTPN1DAGLAPPARGPPARABID
	SCHEMBL5588065	0.89	BID (0.51)	PTPN1DAGLAPPARGPPARABID
	SCHEMBL5589742	0.89	BID (0.51)	PTPN1DAGLAPPARGPPARABID
	SCHEMBL5590353	0.89	BID (0.51)	PTPN1DAGLAPPARGPPARABID
	SCHEMBL5587501	0.87	PTPN1 (0.47)	PTPN1PTPN11PTPN2PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.