SCHEMBL5588307

SCHEMBL5588307

CCc1cc(CC)c(N=C(C)c2ccc(C(C)=Nc3c(CC)cc(CC)cc3CC)o2)c(CC)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 1/20 0.34
BACE1 P56817 1/20 0.34
GAA P10253 2/20 0.33
PLK1 P53350 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TRPA1 O75762 1/20 0.33
AKT1 P31749 1/20 0.33
ALDH1A1 P00352 2/20 0.32
MAPT P10636 1/20 0.32
SIGMAR1 Q99720 5/20 0.32
HDAC4 P56524 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
CA12 O43570 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
PPARG P37231 1/20 0.31
HTT P42858 1/20 0.31
MAPK10 P53779 1/20 0.31
NCOA2 Q15596 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5588302 1.00 PLAU (0.34) PLAUBACE1GAAPLK1MEN1
SCHEMBL14280822 0.84 GABRA1 (0.43) PLAUGAAALDH1A1SIGMAR1
SCHEMBL5590533 0.78 HSPA5 (0.33) PLAUBACE1GAAMEN1KMT2A
SCHEMBL5590532 0.78 HSPA5 (0.33) PLAUBACE1GAAMEN1KMT2A
SCHEMBL5587255 0.76 CYP1A2 (0.40) GAAMEN1KMT2AALDH1A1MAPT
SCHEMBL5587258 0.76 CYP1A2 (0.40) GAAMEN1KMT2AALDH1A1MAPT
SCHEMBL5588100 0.74 CYP1A2 (0.39) GAAMEN1KMT2AALDH1A1MAPT
Hydrochloric Acid SCHEMBL7175784 0.74 CYP1A2 (0.39) GAAMEN1KMT2AALDH1A1MAPT
Hydrochloric Acid SCHEMBL7171124 0.73 CYP1A2 (0.38) GAAMEN1KMT2AALDH1A1MAPT
Hydrochloric Acid SCHEMBL7176032 0.73 CYP1A2 (0.38) GAAMEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US disclosed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP disclosed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US disclosed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP disclosed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 PLAU 3862/4885BACE1 2568/4885GAA 1882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.