SCHEMBL5588730

SCHEMBL5588730

CCCCC1=CC(F)=C(CCCC)C(=O)C1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 17/20 0.40
PTGS2 P35354 4/20 0.40
PTPN1 P18031 1/20 0.39
GLS2 Q9UI32 1/20 0.39
ACHE P22303 1/20 0.37
BACE1 P56817 1/20 0.37
MPEG1 Q2M385 7/20 0.37
XIAP P98170 2/20 0.37
GPR84 Q9NQS5 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
PTGES O14684 1/20 0.37
USP2 O75604 1/20 0.37
ALDH1A1 P00352 1/20 0.37
TP53 P04637 1/20 0.37
CYP2D6 P10635 1/20 0.37
MAPT P10636 1/20 0.37
CYP2C9 P11712 1/20 0.37
HPGD P15428 1/20 0.37
ALOX15 P16050 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5587232 0.78 ALOX5 (0.40) ALOX5PTGS2PTPN1GLS2ACHE
SCHEMBL5588914 0.76 ALOX5 (0.41) ALOX5PTGS2PTPN1GLS2MPEG1
SCHEMBL5587451 0.74 ALOX5 (0.40) ALOX5PTGS2PTPN1GLS2ACHE
SCHEMBL5587817 0.74 ALOX5 (0.41) ALOX5PTGS2GLS2MPEG1
SCHEMBL5587560 0.74 ALOX5 (0.41) ALOX5PTGS2GLS2MPEG1
SCHEMBL5586994 0.73 ALOX5 (0.39) ALOX5MPEG1XIAPGPR84KDM4E
SCHEMBL6206063 0.73 ALOX5 (0.63) ALOX5MPEG1XIAPGPR84KDM4E
SCHEMBL5590643 0.73 ALOX5 (0.40) ALOX5PTGS2GLS2MPEG1
SCHEMBL8846303 0.71 ALOX5 (0.61) ALOX5PTGS2PTPN1GLS2ACHE
SCHEMBL12172151 0.71 ALOX5 (0.47) ALOX5PTGS2PTPN1GLS2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US disclosed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP disclosed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 ALOX5 188/4885PTGS2 3242/4885PTPN1 4679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.