SCHEMBL5589477

SCHEMBL5589477

Cc1c(O)c(O)c(C)c2c1Oc1ccc(Br)c(Br)c1O2

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.39
ALOX12 P18054 2/20 0.39
AHR P35869 3/20 0.36
PRMT1 Q99873 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5586769 0.83 ALOX15 (0.42) ALOX15ALOX12AHRPRMT1
SCHEMBL936968 0.80
SCHEMBL30599776 0.80
SCHEMBL5588910 0.79 AHR (0.58) ALOX15ALOX12AHR
SCHEMBL5590709 0.79 PTGS2 (0.38) ALOX15ALOX12AHRPRMT1
SCHEMBL5588919 0.78 ALOX15 (0.33) ALOX15ALOX12AHR
SCHEMBL5586840 0.77 CYP1A1 (0.34) ALOX15ALOX12
SCHEMBL8714094 0.76 AHR (0.41) ALOX15ALOX12AHR
SCHEMBL8717760 0.76 AHR (0.41) ALOX15ALOX12AHR
SCHEMBL8712723 0.76 AHR (0.41) ALOX15ALOX12AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US disclosed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP disclosed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP disclosed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO disclosed