Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5588400 | 0.93 | ESR1 (0.44) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL29059209 | 0.84 | ESR1 (0.53) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7607111 | 0.81 | THRA (0.48) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL5590437 | 0.81 | ESR1 (0.45) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL5587142 | 0.81 | ESR1 (0.45) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL5588895 | 0.81 | ESR1 (0.45) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL5588941 | 0.81 | ESR1 (0.45) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL5588917 | 0.79 | ESR1 (0.43) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| Hx-1171 SCHEMBL29375871 | 0.78 | ESR1 (0.50) | ESR1ALOX5THRATHRBNR5A1 | |
| Hx-1171 SCHEMBL688955 | 0.78 | ESR1 (0.50) | ESR1ALOX5THRATHRBNR5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247687-B2 | Late transition metal catalysts for olefin polymerization and oligomerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-07-24 | — | — | US | disclosed |
| EP-1521758-B1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2006-05-24 | — | — | EP | disclosed |
| US-20060047094-A1 | Late transition metal catalysts for olefin polymerization and oligomerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-03-02 | — | — | US | disclosed |
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060047094-A1 | Late transition metal catalysts for olefin polymerization and oligomerization | MLX, LOX, LMTK3 | ESR1 1108/4885AKR1C4 2602/4885AKR1C3 2555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.