SCHEMBL5589809

SCHEMBL5589809

COC1=C(C(C)C)C(=O)C(=O)C(C(C)C)=C1OC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25A P30304 9/20 0.44
CDC25B P30305 9/20 0.44
ALDH1A1 P00352 6/20 0.44
MAPT P10636 6/20 0.44
TDP1 Q9NUW8 3/20 0.44
POLB P06746 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
KDM4E B2RXH2 2/20 0.44
LMNA P02545 2/20 0.44
HPGD P15428 2/20 0.44
RAB9A P51151 2/20 0.44
MAP2K7 O14733 1/20 0.44
GMNN O75496 1/20 0.44
TP53 P04637 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
ALOX15 P16050 1/20 0.44
CYP2C19 P33261 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17532554 0.80 CDC25A (0.38) CDC25ACDC25BALDH1A1MAPTTDP1
SCHEMBL8248751 0.75 IDO1 (0.48) CDC25ACDC25BALDH1A1MAPTTDP1
SCHEMBL14179694 0.74 PTPN1 (0.44) CDC25ACDC25BALDH1A1MAPTTDP1
SCHEMBL15944061 0.74 CDC25A (0.52) CDC25ACDC25BALDH1A1MAPTTDP1
SCHEMBL5590269 0.72 CDC25B (0.37) CDC25ACDC25BALDH1A1MAPTTDP1
SCHEMBL3413343 0.71 CDC25A (0.37) CDC25ACDC25BPTPN1
SCHEMBL5590042 0.71 PTPN1 (0.41) CDC25ACDC25BALDH1A1MAPTTDP1
SCHEMBL3420496 0.68 MAPT (0.58) CDC25ACDC25BALDH1A1MAPTTDP1
SCHEMBL5586803 0.66 CDC25A (0.39) CDC25ACDC25BALDH1A1MAPTTDP1
SCHEMBL9222190 0.66 ALDH1A1 (0.36) CDC25ACDC25BALDH1A1MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US disclosed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP disclosed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 CDC25A 1871/4885CDC25B 2427/4885ALDH1A1 2181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.