SCHEMBL5590182

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5589643	0.89	AHR (0.58)	AHRHPGDHSD17B10TSHRCASP1
	SCHEMBL5589319	0.87	AHR (0.37)	AHRHPGDHSD17B10CYP3A4MAPK1
	SCHEMBL5589159	0.85	AHR (0.53)	AHRHPGDHSD17B10TSHRCASP1
	SCHEMBL5588574	0.76	CYP19A1 (0.35)	ALOX15ALOX12
	SCHEMBL5588324	0.75	AHR (0.55)	AHRHPGDCYP3A4MAPK1MEN1
	SCHEMBL5590581	0.73	ALOX15 (0.42)	AHRALOX15ALOX12
	SCHEMBL5590332	0.72	AHR (0.50)	AHRHPGDHSD17B10TSHRCYP3A4
	SCHEMBL5589574	0.72	AHR (0.55)	AHRHPGDHSD17B10TSHRCYP3A4
	SCHEMBL5588060	0.72	AHR (0.64)	AHRHPGDHSD17B10TSHRCASP1
	SCHEMBL5588583	0.71	AHR (0.58)	AHRHPGDHSD17B10TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.