Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA4 | P22459 | 1/20 | 0.33 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.33 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9804280 | 0.81 | — | — | |
| SCHEMBL7259096 | 0.80 | KCNA4 (0.32) | KCNA4KCNA1KCNAB1 | |
| SCHEMBL28642888 | 0.80 | KCNA4 (0.32) | KCNA4KCNA1KCNAB1 | |
| SCHEMBL9619293 | 0.77 | — | — | |
| SCHEMBL28770598 | 0.77 | KDM4E (0.32) | KCNA4KCNA1KCNAB1 | |
| SCHEMBL9619157 | 0.75 | — | — | |
| SCHEMBL9708741 | 0.73 | FFAR3 (0.38) | KCNA4KCNA1KCNAB1 | |
| SCHEMBL9544955 | 0.73 | — | — | |
| SCHEMBL3670104 | 0.72 | — | — | |
| SCHEMBL6581060 | 0.72 | FFAR3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1266899-B1 | Rapamycin hdroxyesters, process for their preparation and pharmaceutical compositions containing them | WYETH CORP (US) | 2007-01-03 | — | — | EP | claimed |
| EP-1216251-B1 | REGIOSELECTIVE SYNTHESIS OF RAPAMYCIN DERIVATIVES | WYETH CORP (US) | 2003-02-26 | — | — | EP | claimed |
| EP-0247472-B1 | PROCESS FOR THE PREPARATION OF CARBOXYLIC ACID DERIVATIVES | BAYER AG (DE) | 1992-02-12 | — | — | EP | disclosed |
| EP-0247472-A2 | Process for the preparation of carboxylic acid derivatives | BAYER AG (DE) | 1987-12-02 | — | — | EP | disclosed |