Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.38 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.37 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.37 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | STAT6 | P42226 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28017602 | 0.90 | FFAR3 (0.35) | FFAR3KCNA4KCNA1KCNAB1MAPK1 | |
| SCHEMBL42141 | 0.81 | FFAR3 (0.52) | FFAR3KCNA4KCNA1KCNAB1MAPK1 | |
| Hydrochloric Acid SCHEMBL15522635 | 0.79 | FFAR3 (0.50) | FFAR3KCNA4KCNA1KCNAB1MAPK1 | |
| SCHEMBL18105045 | 0.78 | ATM (0.38) | MAPK1LMNASMN1; SMN2 | |
| SCHEMBL9708919 | 0.77 | MAPK1 (0.39) | FFAR3MAPK1TP53NFKB1CYP2C19 | |
| SCHEMBL9708626 | 0.74 | FFAR3 (0.32) | FFAR3 | |
| SCHEMBL12731596 | 0.73 | FFAR3 (0.33) | FFAR3KCNA4KCNA1KCNAB1MAPK1 | |
| SCHEMBL9709063 | 0.73 | POLB (0.36) | CYP2C19 | |
| SCHEMBL818086 | 0.73 | POLB (0.36) | CYP2C19 | |
| SCHEMBL9709078 | 0.73 | LMNA (0.31) | MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220034-B1 | MALONATE DERIVATIVES USEFUL AS LIGHT STABILIZERS FOR PLASTICS | ICI AMERICAS INC. (US) | 1992-06-24 | — | — | EP | disclosed |
| US-4701485-A | Malonate-based light stabilizers for plastics | ICI AMERICAS INC. (US) | 1987-10-20 | — | — | US | disclosed |
| EP-0220034-A2 | Malonate derivatives useful as light stabilizers for plastics | ICI AMERICAS INC. (US) | 1987-04-29 | — | — | EP | disclosed |