SCHEMBL5590478

SCHEMBL5590478

CCCCCCCCc1c(O)c(O)c(C(=O)OBr)c(CCCCCCCC)c1CCCCCCCC

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 2/20 0.38
PLA2G5 P39877 2/20 0.38
ALOX5 P09917 5/20 0.38
ESR1 P03372 2/20 0.37
FFAR1 O14842 2/20 0.36
AKR1C4 P17516 1/20 0.35
AKR1C3 P42330 1/20 0.35
AKR1C2 P52895 1/20 0.35
AKR1C1 Q04828 1/20 0.35
TYR P14679 1/20 0.34
BID P55957 1/20 0.34
BCL2L1 Q07817 1/20 0.34
MCL1 Q07820 1/20 0.34
BAK1 Q16611 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5589513 1.00 PLA2G2A (0.38) PLA2G2APLA2G5ALOX5ESR1FFAR1
SCHEMBL5587956 1.00 PLA2G2A (0.38) PLA2G2APLA2G5ALOX5ESR1FFAR1
SCHEMBL5587341 1.00 PLA2G2A (0.38) PLA2G2APLA2G5ALOX5ESR1FFAR1
SCHEMBL5587860 0.98 FFAR1 (0.36) PLA2G2APLA2G5ALOX5ESR1FFAR1
SCHEMBL5589971 0.94 FFAR1 (0.41) PLA2G2APLA2G5ESR1FFAR1AKR1C4
SCHEMBL5589423 0.88 PLA2G2A (0.36) PLA2G2APLA2G5ALOX5ESR1FFAR1
SCHEMBL5590690 0.88 PLA2G2A (0.36) PLA2G2APLA2G5ALOX5ESR1FFAR1
SCHEMBL5589884 0.88 PLA2G2A (0.36) PLA2G2APLA2G5ALOX5ESR1FFAR1
SCHEMBL5587013 0.88 PLA2G2A (0.36) PLA2G2APLA2G5ALOX5ESR1FFAR1
SCHEMBL5588501 0.88 PLA2G2A (0.36) PLA2G2APLA2G5ALOX5ESR1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US disclosed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP disclosed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US disclosed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP disclosed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 PLA2G2A 4233/4885PLA2G5 4231/4885ALOX5 188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.