Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | PPARD | Q03181 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | OTC | P00480 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26605993 | 0.88 | TSHR (0.48) | TSHRPPARDKDM4EMMP2THRB | |
| SCHEMBL282472 | 0.83 | TSHR (0.67) | TSHRPPARDTP53TDP1 | |
| SCHEMBL9654507 | 0.80 | TSHR (0.63) | TSHRPPARDTP53TDP1 | |
| SCHEMBL30529809 | 0.79 | TSHR (0.79) | TSHRPPARDKDM4EMMP2THRB | |
| SCHEMBL1563641 | 0.79 | PPARD (0.56) | TSHRPPARDKDM4EMMP2THRB | |
| SCHEMBL8351172 | 0.77 | PPARD (0.62) | TSHRPPARDTP53TDP1LPAR3 | |
| SCHEMBL4420368 | 0.77 | TSHR (0.43) | TSHRPPARDKDM4EMMP2THRB | |
| SCHEMBL10040020 | 0.76 | TSHR (0.57) | TSHRPPARDTP53TDP1 | |
| Dimethylamine SCHEMBL27510386 | 0.76 | TSHR (0.57) | TSHRPPARDTP53TDP1CA12 | |
| SCHEMBL8862408 | 0.76 | TSHR (0.57) | TSHRPPARDTP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020091253-A1 | Processes for synthesis of cyclic and linear polyamine chelators containing N-monosubstituted coordinating arms | CONCAT, LTD. | 2002-07-11 | — | — | US | claimed |
| CN-116730888-A | Preparation method and application of canthaxanthin | 万华化学集团股份有限公司 | 2023-09-12 | — | — | CN | disclosed |
| US-11046807-B2 | Flame-resistant polymer polyol dispersion | PCC ROKITA SA (PL) | 2021-06-29 | — | — | US | disclosed |
| US-10093688-B2 | Non-aqueous liquid electrolyte, electricity storage device using same, and phosphorus compound used therein | UBE INDUSTRIES, LTD. (JP) | 2018-10-09 | — | — | US | disclosed |
| US-20180223032-A1 | FLAME-RESISTANT POLYMER POLYOL DISPERSION | PCC ROKITA SA (PL) | 2018-08-09 | — | — | US | disclosed |
| EP-3133100-B1 | FLAME-RESISTANT POLYMER POLYOL DISPERSION | PCC ROKITA SA (PL) | 2018-04-18 | — | — | EP | disclosed |
| US-20170275311-A1 | NON-AQUEOUS LIQUID ELECTROLYTE, ELECTRICITY STORAGE DEVICE USING SAME, AND PHOSPHORUS COMPOUND USED THEREIN | UBE INDUSTRIES, LTD. (JP) | 2017-09-28 | — | — | US | disclosed |
| EP-3133100-A1 | FLAME-RESISTANT POLYMER POLYOL DISPERSION | PCC Rokita SA (PL) | 2017-02-22 | — | — | EP | disclosed |
| US-20130059844-A1 | 2-PHENYL SUBSTITUTED IMIDAZOTRIAZINONES AS PHOSPHODIESTERASE INHIBITORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2013-03-07 | — | — | US | disclosed |
| EP-1174431-B1 | 2-Phenyl-substituited Imidazotriazinones as Phoshodiesterase Inhibitors | Bayer Pharma AG (DE) | 2012-05-30 | — | — | EP | disclosed |
| EP-0639197-B1 | EXCITATORY AMINO ACID ANTAGONISTS | GUILFORD PHARM INC (US) | 1996-09-04 | — | — | EP | disclosed |
| US-5428155-A | PH controlled sulfomethylation of 1,4,7,10-tetraazacyclododecane; displacement with sodium cyanide; hydrolysis to symmetrical acetic acid side groups | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1995-06-27 | — | — | US | disclosed |
| EP-0639197-A1 | EXCITATORY AMINO ACID ANTAGONISTS. | GUILFORD PHARM INC (US) | 1995-02-22 | — | — | EP | disclosed |
| EP-0618910-A1 | SYNTHESIS OF POLYAZAMACROCYCLES WITH MORE THAN ONE TYPE OF SIDE-CHAIN CHELATING GROUPS | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1994-10-12 | — | — | EP | disclosed |
| US-5316757-A | MRI contrast agent | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1994-05-31 | — | — | US | disclosed |
| EP-0639197-A4 | EXCITATORY AMINO ACID ANTAGONISTS. | GUILFORD PHARM INC (US) | 1994-02-21 | — | — | EP | disclosed |
| US-5256814-A | Anticonvulsant, analgesic, cognition activator | SCIOS NOVA INC. (US) | 1993-10-26 | — | — | US | disclosed |
| WO-1993012097-A1 | SYNTHESIS OF POLYAZAMACROCYCLES WITH MORE THAN ONE TYPE OF SIDE-CHAIN CHELATING GROUPS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1993-06-24 | — | — | WO | disclosed |
| EP-0495355-A1 | Copolymers of diallylaminoalkylene phosphonates and unsaturated carboxylic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-07-22 | — | — | EP | disclosed |
| WO-1992010099-A1 | EXCITATORY AMINO ACID ANTAGONISTS | NOVA PHARMACEUTICAL CORPORATION (US) | 1992-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130059844-A1 | 2-PHENYL SUBSTITUTED IMIDAZOTRIAZINONES AS PHOSPHODIESTERASE INHIBITORS | PDE3B, PDE3A, PDE2A | TSHR 3349/4885PPARD 1367/4885KDM4E 1131/4885 |
| US-20020091253-A1 | Processes for synthesis of cyclic and linear polyamine chelators containing N-monosubstituted coordinating arms | SRM, SAMHD1, PARN | TSHR 1380/4885PPARD 4624/4885KDM4E 2432/4885 |
| US-20170275311-A1 | NON-AQUEOUS LIQUID ELECTROLYTE, ELECTRICITY STORAGE DEVICE USING SAME, AND PHOSPHORUS COMPOUND USED THEREIN | SCN10A, CACNA2D4, P2RY10 | TSHR 4055/4885PPARD 3581/4885KDM4E 1583/4885 |
| US-10093688-B2 | Non-aqueous liquid electrolyte, electricity storage device using same, and phosphorus compound used therein | SCN10A, CACNA2D4, P2RY10 | TSHR 3923/4885PPARD 3262/4885KDM4E 1765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.