Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4510449 | 0.84 | CA12 (0.39) | ALDH1A1CA1CA12CA9PKM | |
| SCHEMBL241884 | 0.73 | CA1 (0.52) | ALDH1A1GAACA1CA12CA9 | |
| SCHEMBL6906905 | 0.72 | CA1 (0.50) | ALDH1A1GAACA1CA12CA9 | |
| SCHEMBL18289524 | 0.72 | CA1 (0.50) | ALDH1A1GAACA1CA12CA9 | |
| SCHEMBL11564574 | 0.71 | KDM4E (0.48) | MAPTCA1CA12CA9PKM | |
| SCHEMBL15467048 | 0.71 | CA12 (0.44) | ALDH1A1GAACA1CA12CA9 | |
| SCHEMBL27602739 | 0.70 | CA12 (0.46) | ALDH1A1GAACA1CA12CA9 | |
| SCHEMBL483847 | 0.69 | ALDH1A1 (0.50) | ALDH1A1GAACA1CA12CA9 | |
| Water SCHEMBL7788572 | 0.69 | CA1 (0.50) | ALDH1A1GAACA1CA12CA9 | |
| Ethylene SCHEMBL3466431 | 0.69 | CA1 (0.50) | ALDH1A1GAACA1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034277-A1 | ARYL SUBSTITUTED IMIDAZO [4,5-C] PYRIDINE COMPOUNDS AS C3A RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | disclosed |