Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27745813 | 0.70 | — | — | |
| SCHEMBL18263407 | 0.69 | CTSC (0.54) | — | |
| SCHEMBL28613679 | 0.62 | HIF1A (0.39) | HIF1ACA1CA2 | |
| SCHEMBL6221887 | 0.60 | HIF1A (0.41) | HIF1ACA1CA2 | |
| SCHEMBL11141890 | 0.59 | KDM4E (0.36) | — | |
| SCHEMBL2639661 | 0.59 | — | — | |
| SCHEMBL8234550 | 0.58 | — | — | |
| SCHEMBL29956584 | 0.57 | — | — | |
| SCHEMBL5968403 | 0.56 | MCL1 (0.40) | — | |
| SCHEMBL16171889 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007059116-A2 | GELDANAMYCIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | ABRAXIS BIOSCIENCE, INC. (US) | 2007-05-24 | — | — | WO | disclosed |