Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | CASP1 | P29466 | 5/20 | 0.37 |
| ▸ | CASP7 | P55210 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CASR | P41180 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 4/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1941549 | 0.87 | CYP1A2 (0.47) | PTGER4CYP1A2ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL5591600 | 0.83 | MAPT (0.39) | PTGER4CYP1A2ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL5598194 | 0.81 | PTGER4 (0.41) | PTGER4 | |
| SCHEMBL14521250 | 0.76 | KMT2A (0.40) | PTGER4CYP3A4CYP2C9CYP2D6KMT2A | |
| SCHEMBL5591608 | 0.70 | PTGER4 (0.59) | PTGER4CYP1A2ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL1941058 | 0.70 | CYP1A2 (0.44) | PTGER4CYP1A2ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL5591693 | 0.70 | HPGD (0.35) | PTGER4CYP1A2ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL1942913 | 0.68 | GLP1R (0.45) | PTGER4CYP1A2ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL14521394 | 0.67 | PTGER4 (0.41) | PTGER4ALDH1A1TP53BRD4 | |
| SCHEMBL2496199 | 0.67 | CASR (0.69) | CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007072142-A2 | BENZIMIDAZOLE-5-CARBOXAMIDE DERIVATIVES | PFIZER JAPAN INC. (JP) | 2007-06-28 | — | — | WO | disclosed |