Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GLP1R | P43220 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1941549 | 0.90 | CYP1A2 (0.47) | LMNASTAT3HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5598246 | 0.85 | LMNA (0.41) | MAPTLMNAPOLBSTAT3HTT | |
| SCHEMBL5591571 | 0.83 | PTGER4 (0.38) | LMNASMN1; SMN2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL5598558 | 0.81 | PPARA (0.43) | ALDH1A1CYP1A2CYP3A4CYP2C9CASP1 | |
| SCHEMBL14521393 | 0.79 | PTGER4 (0.39) | MAPTLMNAPOLBSTAT3HTT | |
| SCHEMBL5591586 | 0.79 | LMNA (0.40) | MAPTLMNAPOLBSTAT3HTT | |
| SCHEMBL14522391 | 0.77 | STING1 (0.42) | MAPTLMNAPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL14522385 | 0.76 | USP2 (0.44) | MAPTLMNAPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL5598461 | 0.75 | HSD17B10 (0.44) | MAPTLMNASMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL14522388 | 0.74 | KMT2A (0.35) | MAPTLMNAPOLBSTAT3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007072142-A2 | BENZIMIDAZOLE-5-CARBOXAMIDE DERIVATIVES | PFIZER JAPAN INC. (JP) | 2007-06-28 | — | — | WO | disclosed |