Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 16/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31393026 | 0.86 | ALDH1A1 (0.49) | ALDH1A1HSD17B10MAPK1TSHRCYP1A2 | |
| SCHEMBL2209684 | 0.86 | ALDH1A1 (0.67) | ALDH1A1HSD17B10MAPK1TSHRCYP1A2 | |
| SCHEMBL2696995 | 0.78 | ALDH1A1 (0.55) | ALDH1A1HSD17B10MAPK1TSHRCYP1A2 | |
| SCHEMBL27180184 | 0.73 | ALDH1A1 (0.57) | ALDH1A1HSD17B10MAPK1TSHRCYP1A2 | |
| SCHEMBL25284932 | 0.72 | ALDH1A1 (0.56) | ALDH1A1HSD17B10MAPK1TSHRCYP1A2 | |
| SCHEMBL16134952 | 0.72 | ALDH1A1 (0.69) | ALDH1A1HSD17B10MAPK1TSHRCYP1A2 | |
| SCHEMBL15979042 | 0.70 | ALDH1A1 (0.64) | ALDH1A1HSD17B10MAPK1TSHRCYP1A2 | |
| SCHEMBL2206344 | 0.70 | ALDH1A1 (0.60) | ALDH1A1HSD17B10MAPK1TSHRCYP1A2 | |
| SCHEMBL14358107 | 0.70 | ALDH1A1 (0.56) | ALDH1A1HSD17B10MAPK1TSHRCYP1A2 | |
| SCHEMBL24423111 | 0.69 | ALDH1A1 (0.71) | ALDH1A1HSD17B10MAPK1TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007113548-A1 | NAPHTHYRIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2007-10-11 | — | — | WO | disclosed |