Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5591950 | 0.88 | HRH3 (0.43) | HRH3ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL5591868 | 0.86 | APP (0.50) | HRH3 | |
| SCHEMBL5598791 | 0.80 | CYP19A1 (0.42) | HRH3ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL7187375 | 0.78 | L3MBTL1 (0.51) | HRH3ALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL5591800 | 0.76 | HRH3 (0.49) | HRH3ALDH1A1KDM4ESMN1; SMN2CYP2D6 | |
| SCHEMBL23507365 | 0.73 | KDM4E (0.70) | HRH3ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL5591961 | 0.72 | APP (0.48) | HRH3ALDH1A1KDM4E | |
| SCHEMBL807235 | 0.72 | KDM4E (0.68) | HRH3ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL31010255 | 0.72 | KDM4E (0.68) | HRH3ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL23882852 | 0.70 | TOP2A (0.43) | ALDH1A1MEN1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007104696-A1 | ANTIMALARIAL AGENTS HAVING POLYAROMATIC STRUCTURE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-09-20 | — | — | WO | disclosed |