Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592048 | 0.78 | HRH3 (0.43) | HRH3MEN1ALDH1A1KMT2ACYP2D6 | |
| SCHEMBL13356470 | 0.77 | SLC2A1 (0.59) | MEN1ALDH1A1KMT2APOLBCYP2D6 | |
| SCHEMBL13356412 | 0.77 | SLC2A1 (0.59) | MEN1ALDH1A1KMT2APOLBCYP2D6 | |
| SCHEMBL6665709 | 0.77 | LOXL2 (0.55) | ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL11904339 | 0.77 | LOXL2 (0.46) | ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL12434732 | 0.76 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1POLBCYP2C19 | |
| SCHEMBL7193788 | 0.76 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1POLBCYP2C19 | |
| SCHEMBL7356799 | 0.75 | CYP2D6 (0.45) | ALDH1A1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL6110522 | 0.73 | HRH3 (0.44) | HRH3MEN1ALDH1A1KMT2ACYP2D6 | |
| SCHEMBL4278256 | 0.72 | NCF1 (0.50) | MEN1ALDH1A1KMT2ACYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6646135-B1 | Alpha ketoesters and alpha ketolactones to produce an alpha hydroxy carbonyl compound. | ROCHE VITAMINS INC. | 2003-11-11 | — | — | US | disclosed |
| EP-1063224-B1 | Continuous hydrogenation process | HOFFMANN LA ROCHE (CH) | 2003-06-25 | — | — | EP | disclosed |
| EP-1063224-A1 | Continuous hydrogenation process | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-27 | — | — | EP | disclosed |