Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.41 |
| ▸ | KDR | P35968 | 4/20 | 0.41 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | CSF1R | P07333 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4655471 | 0.84 | MET (0.49) | METALDH1A1PDGFRBKDRFLT3 | |
| SCHEMBL2173413 | 0.79 | PDGFRB (0.62) | METKDM4EALDH1A1HSD17B10PDGFRB | |
| SCHEMBL2174885 | 0.72 | ALDH1A1 (0.53) | METKDM4EALDH1A1HSD17B10PDGFRB | |
| SCHEMBL4371203 | 0.72 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10GAAMEN1 | |
| SCHEMBL2172465 | 0.72 | PDGFRB (0.62) | METKDM4EALDH1A1HSD17B10PDGFRB | |
| SCHEMBL2175177 | 0.70 | PDGFRB (0.61) | METKDM4EALDH1A1HSD17B10PDGFRB | |
| SCHEMBL8296534 | 0.70 | MAOB (0.57) | MEN1KMT2AMAPT | |
| SCHEMBL30581779 | 0.69 | EGFR (0.51) | KDM4EALDH1A1HSD17B10GAAMEN1 | |
| SCHEMBL2173834 | 0.69 | EGFR (0.51) | KDM4EALDH1A1HSD17B10GAAMEN1 | |
| SCHEMBL2177709 | 0.69 | PDGFRB (0.62) | PDGFRBKDRFLT3CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007113548-A1 | NAPHTHYRIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2007-10-11 | — | — | WO | disclosed |