Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 16/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3569483 | 0.90 | REN (0.47) | REN | |
| SCHEMBL12991819 | 0.90 | REN (0.47) | REN | |
| SCHEMBL3569485 | 0.90 | REN (0.47) | REN | |
| SCHEMBL5616690 | 0.89 | REN (0.45) | RENLMNA | |
| SCHEMBL5610964 | 0.88 | REN (0.46) | RENNPC1RAB9ACTSATDP1 | |
| SCHEMBL5610962 | 0.88 | REN (0.46) | RENNPC1RAB9ACTSATDP1 | |
| SCHEMBL4292328 | 0.87 | REN (0.52) | REN | |
| SCHEMBL4292326 | 0.87 | REN (0.52) | REN | |
| SCHEMBL4295733 | 0.87 | REN (0.52) | REN | |
| SCHEMBL4295728 | 0.87 | REN (0.52) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007117482-A2 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-10-18 | — | — | WO | claimed |
| WO-2007117482-A2 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-10-18 | — | — | WO | disclosed |