Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592235 | 0.72 | CHRM2 (0.45) | — | |
| SCHEMBL29795816 | 0.64 | KMT2A (0.51) | MEN1POLBKMT2AHTTHPGD | |
| SCHEMBL9517659 | 0.63 | POLB (0.55) | MEN1POLBKMT2AHTTHPGD | |
| SCHEMBL6273408 | 0.63 | MEN1 (0.55) | MEN1POLBKMT2A | |
| SCHEMBL7229004 | 0.63 | MEN1 (0.55) | MEN1POLBKMT2A | |
| SCHEMBL4531618 | 0.63 | MEN1 (0.55) | MEN1POLBKMT2AHTTHPGD | |
| SCHEMBL717026 | 0.63 | MEN1 (0.60) | MEN1POLBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL22539014 | 0.62 | MEN1 (0.42) | MEN1POLBKMT2AHTTHPGD | |
| SCHEMBL11052023 | 0.62 | MEN1 (0.53) | MEN1POLBKMT2AHTTHPGD | |
| SCHEMBL718406 | 0.62 | MGLL (0.61) | MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |