Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592201 | 0.72 | MEN1 (0.41) | — | |
| SCHEMBL5592226 | 0.71 | HTR1A (0.43) | CHRM2CHRM4CHRM5CHRM1DRD2 | |
| SCHEMBL4884715 | 0.70 | FUCA1 (0.49) | ACHE | |
| SCHEMBL40679 | 0.69 | POLB (0.61) | — | |
| SCHEMBL7620067 | 0.69 | CHRM2 (0.80) | CHRM2CHRM4CHRM5CHRM1DRD2 | |
| SCHEMBL16775256 | 0.67 | FUCA1 (0.64) | ACHE | |
| SCHEMBL16759827 | 0.67 | FUCA1 (0.64) | ACHE | |
| SCHEMBL4001399 | 0.67 | SIGMAR1 (0.50) | DRD2DRD4DRD3 | |
| SCHEMBL13102792 | 0.67 | FUCA1 (0.51) | ACHE | |
| SCHEMBL4619365 | 0.67 | FUCA1 (0.51) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |