Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 7/20 | 0.57 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.57 |
| ▸ | BRD4 | O60885 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | IDH1 | O75874 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5188946 | 0.85 | CYP11B1 (0.46) | CYP11B1CYP11B2BRD4TDP1L3MBTL1 | |
| SCHEMBL5610972 | 0.84 | CYP11B1 (0.60) | CYP11B1CYP11B2BRD4POLBMAPT | |
| SCHEMBL2508169 | 0.83 | BRD4 (0.51) | CYP11B1CYP11B2BRD4KDM4ELMNA | |
| SCHEMBL2508166 | 0.83 | BRD4 (0.51) | CYP11B1CYP11B2BRD4KDM4ELMNA | |
| SCHEMBL8936715 | 0.81 | CYP11B1 (0.58) | CYP11B1CYP11B2BRD4KDM4ELMNA | |
| SCHEMBL10945622 | 0.81 | CYP11B1 (0.57) | CYP11B1CYP11B2BRD4KDM4ELMNA | |
| SCHEMBL4290436 | 0.81 | CYP11B1 (0.62) | CYP11B1CYP11B2KDM4EPOLBCYP19A1 | |
| SCHEMBL2509182 | 0.79 | BRD4 (0.50) | CYP11B1CYP11B2BRD4KDM4ELMNA | |
| SCHEMBL2509183 | 0.79 | BRD4 (0.50) | CYP11B1CYP11B2BRD4KDM4ELMNA | |
| SCHEMBL30168127 | 0.78 | CYP11B1 (0.62) | CYP11B1CYP11B2BRD4KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079800-A1 | IMIDAZOLYLMETHYL-SUBSTITUTED DEVELOPERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-07-19 | — | — | WO | claimed |
| WO-2007079800-A1 | IMIDAZOLYLMETHYL-SUBSTITUTED DEVELOPERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-07-19 | — | — | WO | disclosed |
| WO-2007079800-A1 | IMIDAZOLYLMETHYL-SUBSTITUTED DEVELOPERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-07-19 | — | — | WO | disclosed |