Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PARL | Q9H300 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5592220 | 0.99 | HTR1A (0.52) | HTR1AALDH1A1LMNASMN1; SMN2PARL | |
| SCHEMBL853378 | 0.77 | ALDH1A1 (0.58) | ALDH1A1LMNASMN1; SMN2HTTKCNJ1 | |
| SCHEMBL1519692 | 0.76 | ALDH1A1 (0.69) | ALDH1A1LMNASMN1; SMN2PARLHTT | |
| SCHEMBL7535254 | 0.74 | HTT (0.56) | ALDH1A1LMNASMN1; SMN2PARLHTT | |
| SCHEMBL21681941 | 0.73 | ALDH1A1 (0.74) | ALDH1A1LMNASMN1; SMN2PARLHTT | |
| SCHEMBL7485956 | 0.73 | ALDH1A1 (0.79) | ALDH1A1LMNASMN1; SMN2HTTKMT2A | |
| SCHEMBL5726074 | 0.72 | ATM (0.63) | ALDH1A1LMNASMN1; SMN2HTTKMT2A | |
| SCHEMBL12626953 | 0.72 | KMT2A (0.63) | ALDH1A1LMNASMN1; SMN2PARLHTT | |
| SCHEMBL3691866 | 0.72 | ALDH1A1 (0.82) | ALDH1A1LMNASMN1; SMN2HTTKMT2A | |
| SCHEMBL1269605 | 0.72 | ALDH1A1 (0.82) | ALDH1A1LMNASMN1; SMN2HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | claimed |
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |