Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 18/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.37 |
| ▸ | DRD2 | P14416 | 5/20 | 0.36 |
| ▸ | DRD4 | P21917 | 5/20 | 0.36 |
| ▸ | DRD3 | P35462 | 5/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5592380 | 0.99 | HTR7 (0.40) | HTR7CHRM1ICAM1CHRM2CHRM4 | |
| SCHEMBL5592133 | 0.74 | CHRM1 (0.52) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL5592379 | 0.73 | HTR7 (0.46) | HTR7CHRM1CHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL5599735 | 0.72 | HTR7 (0.45) | HTR7CHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL27508560 | 0.71 | HTR7 (0.51) | HTR7CHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL5599483 | 0.71 | HTR7 (0.44) | HTR7CHRM1CHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL27470920 | 0.70 | HTR7 (0.50) | HTR7CHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL13102870 | 0.69 | HTT (0.61) | ICAM1DRD4 | |
| SCHEMBL13102964 | 0.68 | CNR1 (0.36) | ICAM1 | |
| SCHEMBL5592381 | 0.68 | CHRM1 (0.44) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | claimed |
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |