Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 19/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592142 | 0.84 | ADRA1D (0.65) | CHRM1ALDH1A1ADRA1AADRA1BMCHR1 | |
| SCHEMBL5592381 | 0.81 | CHRM1 (0.44) | CHRM1ALDH1A1 | |
| SCHEMBL16795225 | 0.81 | MAPK1 (0.50) | ALDH1A1ADRA1AADRA1B | |
| SCHEMBL3462094 | 0.76 | ADRA1D (0.47) | ALDH1A1ADRA1AADRA1B | |
| SCHEMBL5592308 | 0.74 | HTR7 (0.41) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| Hydrochloric Acid SCHEMBL5592380 | 0.73 | HTR7 (0.40) | CHRM1CHRM2CHRM4CHRM5DRD2 | |
| SCHEMBL1921058 | 0.72 | KMT2A (0.47) | ADRA1AADRA1B | |
| SCHEMBL16446567 | 0.71 | SIGMAR1 (0.44) | ADRA1AADRA1B | |
| SCHEMBL19924787 | 0.71 | SIGMAR1 (0.44) | CHRM3ADRA1AADRA1B | |
| SCHEMBL4437678 | 0.71 | SIGMAR1 (0.44) | ALDH1A1DRD2ADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | claimed |
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |