Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 9/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR1E | P28566 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5836154 | 0.88 | MEN1 (0.53) | TMEM97SIGMAR1HTR1AADRA2AADRA2B | |
| SCHEMBL1949475 | 0.87 | HPGD (0.56) | TMEM97SIGMAR1HTR1AADRA2AADRA2B | |
| SCHEMBL3767269 | 0.85 | TMEM97 (0.47) | TMEM97SIGMAR1HTR1AADRA2AADRA2B | |
| SCHEMBL6323472 | 0.85 | MEN1 (0.48) | TMEM97SIGMAR1HTR1AADRA2AADRA2B | |
| SCHEMBL21800330 | 0.80 | TMEM97 (0.60) | TMEM97SIGMAR1HTR1AADRA2AADRA2B | |
| SCHEMBL5592390 | 0.80 | TMEM97 (0.46) | TMEM97SIGMAR1HTR1AADRA2AADRA2B | |
| SCHEMBL5592215 | 0.80 | ALDH1A1 (0.43) | TMEM97SIGMAR1HTR1AADRA2AADRA2B | |
| SCHEMBL19960792 | 0.79 | SMN1; SMN2 (0.45) | TMEM97SIGMAR1HTR1AADRA2AADRA2B | |
| SCHEMBL4694452 | 0.79 | HRH3 (0.50) | HRH1HRH3SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2674901 | 0.79 | MEN1 (0.51) | TMEM97SIGMAR1HTR1AADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007057742-A2 | NOVEL PIPERAZINONE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2007-05-24 | — | — | WO | disclosed |