Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 10/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14605987 | 0.89 | HSD11B1 (0.65) | HSD11B1ALDH1A1LMNATSHRRAB9A | |
| SCHEMBL14605771 | 0.88 | HSD11B1 (0.57) | HSD11B1ALDH1A1LMNATSHRRAB9A | |
| SCHEMBL9477798 | 0.87 | HDAC1 (0.52) | HSD11B1ALDH1A1LMNATSHRRAB9A | |
| SCHEMBL12761278 | 0.78 | HDAC1 (0.54) | ALDH1A1LMNATSHRRAB9AHDAC1 | |
| SCHEMBL5592781 | 0.77 | ALDH1A1 (0.59) | ALDH1A1LMNATSHRRAB9AHDAC1 | |
| SCHEMBL4407027 | 0.76 | ALDH1A1 (0.62) | ALDH1A1LMNATSHRHDAC1HDAC6 | |
| SCHEMBL96819 | 0.76 | ALDH1A1 (0.57) | ALDH1A1LMNATSHRRAB9AHDAC1 | |
| SCHEMBL96820 | 0.76 | ALDH1A1 (0.57) | ALDH1A1LMNATSHRRAB9AHDAC1 | |
| SCHEMBL15117306 | 0.75 | ALDH1A1 (0.51) | ALDH1A1LMNATSHRRAB9AHDAC1 | |
| SCHEMBL3096693 | 0.75 | HDAC1 (0.52) | ALDH1A1LMNATSHRRAB9AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029021-A1 | 1,5-SUBSTITUTED TETRAZOLES AS THERAPEUTIC COMPOUNDS | THE UNIVERSITY OF EDINBURGH (GB) | 2007-03-15 | — | — | WO | disclosed |
| WO-2007029021-A1 | 1,5-SUBSTITUTED TETRAZOLES AS THERAPEUTIC COMPOUNDS | THE UNIVERSITY OF EDINBURGH (GB) | 2007-03-15 | — | — | WO | disclosed |