Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.57 |
| ▸ | CTSS | P25774 | 2/20 | 0.57 |
| ▸ | CTSK | P43235 | 2/20 | 0.57 |
| ▸ | CTSB | P07858 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 6/20 | 0.34 |
| ▸ | HTR1A | P08908 | 5/20 | 0.34 |
| ▸ | HTR2A | P28223 | 5/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | WNT1 | P04628 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592638 | 0.96 | CTSL (0.57) | CTSLCTSSCTSKCTSBDRD2 | |
| SCHEMBL5592907 | 0.93 | CTSL (0.61) | CTSLCTSSCTSKCTSBDRD4 | |
| SCHEMBL8243570 | 0.92 | CTSL (0.67) | CTSLCTSSCTSKCTSBHDAC1 | |
| SCHEMBL5592917 | 0.92 | CTSL (0.58) | CTSLCTSSCTSKCTSBDRD4 | |
| SCHEMBL5592751 | 0.91 | CTSL (0.59) | CTSLCTSSCTSKCTSBDRD4 | |
| SCHEMBL5592666 | 0.90 | CTSL (0.61) | CTSLCTSSCTSKCTSBDRD4 | |
| SCHEMBL5592870 | 0.90 | CTSL (0.61) | CTSLCTSSCTSKCTSBDRD4 | |
| SCHEMBL5592654 | 0.89 | CTSL (0.61) | CTSLCTSSCTSKCTSBDRD4 | |
| SCHEMBL5592895 | 0.88 | CTSL (0.60) | CTSLCTSSCTSKCTSBACKR3 | |
| Trifluoroacetic Acid SCHEMBL5592808 | 0.88 | CTSL (0.56) | CTSLCTSSCTSKCTSBDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025775-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | claimed |