Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.60 |
| ▸ | CTSB | P07858 | 1/20 | 0.60 |
| ▸ | CTSS | P25774 | 1/20 | 0.60 |
| ▸ | CTSK | P43235 | 1/20 | 0.60 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.41 |
| ▸ | WNT1 | P04628 | 3/20 | 0.40 |
| ▸ | GSK3B | P49841 | 3/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | CLK3 | P49761 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593161 | 0.99 | CTSL (0.60) | CTSLCTSBCTSSCTSKPTGER1 | |
| SCHEMBL5592666 | 0.97 | CTSL (0.61) | CTSLCTSBCTSSCTSKPTGER1 | |
| SCHEMBL5592654 | 0.96 | CTSL (0.61) | CTSLCTSBCTSSCTSKPTGER1 | |
| SCHEMBL5592751 | 0.95 | CTSL (0.59) | CTSLCTSBCTSSCTSKPTGER1 | |
| Trifluoroacetic Acid SCHEMBL5592876 | 0.95 | CTSL (0.55) | CTSLCTSBCTSSCTSKPTGER1 | |
| Trifluoroacetic Acid SCHEMBL5593235 | 0.94 | CTSL (0.55) | CTSLCTSBCTSSCTSKPTGER1 | |
| SCHEMBL8244881 | 0.93 | CTSL (0.58) | CTSLCTSBCTSSCTSKPTGER1 | |
| SCHEMBL5592870 | 0.92 | CTSL (0.61) | CTSLCTSBCTSSCTSKPTGER1 | |
| SCHEMBL5592907 | 0.92 | CTSL (0.61) | CTSLCTSBCTSSCTSKPTGER1 | |
| Trifluoroacetic Acid SCHEMBL5593218 | 0.92 | CTSL (0.56) | CTSLCTSBCTSSCTSKPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025775-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | disclosed |
| WO-2007025775-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | disclosed |
| WO-2007025776-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | disclosed |