Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.62 |
| ▸ | BPTF | Q12830 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | SDHB | P21912 | 4/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | STAT3 | P40763 | 2/20 | 0.60 |
| ▸ | STAT1 | P42224 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.60 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | CDC7 | O00311 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592890 | 0.88 | BPTF (0.58) | KMT2AMEN1NTSR1BPTFLMNA | |
| SCHEMBL5593055 | 0.84 | BPTF (0.61) | KMT2AMEN1BPTFLMNASDHB | |
| SCHEMBL5592833 | 0.82 | BPTF (0.63) | KMT2AMEN1BPTFLMNASDHB | |
| SCHEMBL5593130 | 0.81 | KMT2A (0.67) | KMT2AMEN1BPTFLMNASDHB | |
| SCHEMBL5593337 | 0.80 | SDHB (0.72) | KMT2AMEN1BPTFLMNASDHB | |
| SCHEMBL7532076 | 0.80 | BPTF (0.65) | KMT2AMEN1BPTFLMNASDHB | |
| SCHEMBL5593297 | 0.79 | SDHB (0.68) | KMT2AMEN1BPTFLMNASDHB | |
| SCHEMBL30032821 | 0.79 | MEN1 (0.88) | KMT2AMEN1NTSR1LMNANPSR1 | |
| SCHEMBL5593019 | 0.78 | BPTF (0.58) | KMT2AMEN1BPTFLMNASDHB | |
| SCHEMBL5593117 | 0.78 | KMT2A (0.71) | KMT2AMEN1BPTFLMNASDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007074238-A2 | NOVEL N-ALK-(E)-YLIDENE-N'-PYRIMIDIN-2-YL HYDRAZINE DERIVATIVES AND USE THEREOF AS CYTOPROTECTIVE DRUGS | TROPHOS (FR) | 2007-07-05 | — | — | WO | disclosed |