Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | CTSB | P07858 | 1/20 | 0.56 |
| ▸ | CTSS | P25774 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 1/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.43 |
| ▸ | GPR6 | P46095 | 4/20 | 0.38 |
| ▸ | WNT1 | P04628 | 3/20 | 0.37 |
| ▸ | GSK3B | P49841 | 3/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | CLK3 | P49761 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5592876 | 0.97 | CTSL (0.55) | CTSLCTSBCTSSCTSKSLC2A1 | |
| Trifluoroacetic Acid SCHEMBL5592935 | 0.97 | CTSL (0.55) | CTSLCTSBCTSSCTSKSLC2A1 | |
| Trifluoroacetic Acid SCHEMBL5593235 | 0.96 | CTSL (0.55) | CTSLCTSBCTSSCTSKSLC2A1 | |
| SCHEMBL5592666 | 0.95 | CTSL (0.61) | CTSLCTSBCTSSCTSKWNT1 | |
| Trifluoroacetic Acid SCHEMBL5592808 | 0.94 | CTSL (0.56) | CTSLCTSBCTSSCTSKSLC2A1 | |
| SCHEMBL5592654 | 0.94 | CTSL (0.61) | CTSLCTSBCTSSCTSKWNT1 | |
| Trifluoroacetic Acid SCHEMBL5592810 | 0.93 | CTSL (0.53) | CTSLCTSBCTSSCTSKSLC2A1 | |
| SCHEMBL5592895 | 0.92 | CTSL (0.60) | CTSLCTSBCTSSCTSKSLC2A1 | |
| SCHEMBL5592751 | 0.92 | CTSL (0.59) | CTSLCTSBCTSSCTSKWNT1 | |
| SCHEMBL5593161 | 0.91 | CTSL (0.60) | CTSLCTSBCTSSCTSKSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025775-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | claimed |