Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4641168 | 0.97 | LMNA (0.35) | LMNAKDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL5592918 | 0.93 | LMNA (0.39) | LMNAKDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL4639468 | 0.93 | KDM4E (0.40) | LMNAKDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL4641214 | 0.92 | LMNA (0.39) | LMNAKDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL4639925 | 0.89 | KDM4E (0.41) | LMNAKDM4EHSD17B10USP2MAPT | |
| SCHEMBL4639709 | 0.88 | LMNA (0.37) | LMNAKDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL4641365 | 0.87 | LMNA (0.38) | LMNAKDM4EHSD17B10RAB9AUSP2 | |
| SCHEMBL4639660 | 0.86 | KDM4E (0.41) | LMNAKDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL5592764 | 0.85 | PARP1 (0.39) | LMNAKDM4EHSD17B10USP2MAPT | |
| SCHEMBL4640052 | 0.85 | KDM4E (0.46) | LMNAKDM4EHSD17B10NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058338-A9 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMA CO LTD (JP) | 2007-11-01 | — | — | WO | disclosed |