Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CEL | P19835 | 2/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | PTPRF | P10586 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10444678 | 0.97 | — | — | |
| SCHEMBL8626050 | 0.92 | — | — | |
| SCHEMBL6238652 | 0.76 | KMT2A (0.36) | CELDAOPTPN1PTPRCPTPRF | |
| SCHEMBL13592856 | 0.72 | KDM4E (0.39) | CELDAOMAOAMAOB | |
| SCHEMBL1075919 | 0.72 | TDO2 (0.30) | — | |
| SCHEMBL304318 | 0.72 | CEL (0.33) | CELDAOPTPN1PTPRCPTPRF | |
| SCHEMBL14620427 | 0.72 | CEL (0.33) | CELDAOPTPN1PTPRCPTPRF | |
| SCHEMBL14620035 | 0.72 | CEL (0.33) | CELDAOPTPN1PTPRCPTPRF | |
| SCHEMBL1898536 | 0.67 | PTPN1 (0.44) | CELDAOPTPN1PTPRCPTPRF | |
| SCHEMBL10679447 | 0.67 | KMT2A (0.34) | CELPTPN1PTPRCPTPRFCDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |