Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | MMP12 | P39900 | 3/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | STS | P08842 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SCN4A | P35499 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592954 | 0.80 | JMJD6 (0.44) | JMJD6KMT2APOLBTDP1SMN1; SMN2 | |
| SCHEMBL8113035 | 0.72 | MMP9 (0.55) | MMP9MMP12MMP1MMP2STS | |
| SCHEMBL28074789 | 0.70 | SCN4A (0.38) | SCN4AMAPTALDH1A1 | |
| SCHEMBL6607433 | 0.69 | SCN4A (0.40) | LMNASCN4ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4188566 | 0.69 | SCN4A (0.45) | KMT2ATDP1SCN4ASMN1; SMN2RAB9A | |
| SCHEMBL5787901 | 0.69 | KDM4C (0.37) | KMT2ASCN4ASMN1; SMN2MEN1RAB9A | |
| SCHEMBL925233 | 0.69 | MMP9 (0.43) | JMJD6MMP9MMP12MMP1MMP2 | |
| SCHEMBL8333853 | 0.68 | MEN1 (0.51) | MMP9MMP12MMP1MMP2STS | |
| SCHEMBL5592749 | 0.68 | MMP9 (0.54) | MMP9MMP12MMP1MMP2STS | |
| SCHEMBL27433093 | 0.68 | PKM (0.52) | MMP9MMP12MMP1MMP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007009690-A1 | HETEROCYCLYL-SUBSTITUTED PYRAZOLINE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A (ES) | 2007-01-25 | — | — | WO | claimed |