Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CTRC | Q99895 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13133556 | 0.89 | MAPT (0.58) | KDM4EMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL5592931 | 0.87 | KDM4E (0.52) | KDM4EMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL7521036 | 0.84 | KDM4E (0.56) | KDM4EMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL5593150 | 0.83 | MEN1 (0.66) | KDM4EMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL5593348 | 0.81 | MAPT (0.51) | KDM4EMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL5593018 | 0.80 | ACACA (0.57) | KDM4EMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL15453227 | 0.80 | MEN1 (0.66) | KDM4EMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL29620538 | 0.80 | MEN1 (0.66) | KDM4EMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL15395065 | 0.80 | MEN1 (0.83) | KDM4EMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL16716532 | 0.80 | MEN1 (0.66) | KDM4EMEN1KMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007074238-A2 | NOVEL N-ALK-(E)-YLIDENE-N'-PYRIMIDIN-2-YL HYDRAZINE DERIVATIVES AND USE THEREOF AS CYTOPROTECTIVE DRUGS | TROPHOS (FR) | 2007-07-05 | — | — | WO | disclosed |