Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEK | Q02763 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.41 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4420790 | 0.88 | MEN1 (0.55) | TEKMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL5604132 | 0.87 | TEK (0.45) | TEKALDH1A1HTTBRAFSMN1; SMN2 | |
| SCHEMBL4417829 | 0.86 | TEK (0.45) | TEKBRAF | |
| SCHEMBL4418552 | 0.86 | MAPK14 (0.44) | TEKMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4408316 | 0.85 | MAPK14 (0.49) | BRAFNAMPTSMN1; SMN2 | |
| SCHEMBL4416214 | 0.85 | MAPK14 (0.43) | TEKMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4410250 | 0.84 | TEK (0.51) | TEKMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4412491 | 0.84 | TEK (0.57) | TEKMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4410129 | 0.84 | MEN1 (0.44) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL14473151 | 0.83 | TEK (0.52) | TEKMEN1KMT2ALMNABRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |