Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4280199 | 0.89 | TSHR (0.41) | TSHRKDM4EHSD17B10ALDH1A1MAPT | |
| SCHEMBL19066427 | 0.89 | TSHR (0.41) | TSHRKDM4EHSD17B10ALDH1A1MAPT | |
| SCHEMBL17037230 | 0.89 | TSHR (0.41) | TSHRKDM4EHSD17B10ALDH1A1MAPT | |
| SCHEMBL4271714 | 0.89 | TSHR (0.41) | TSHRKDM4EHSD17B10ALDH1A1MAPT | |
| SCHEMBL17243832 | 0.86 | TSHR (0.53) | TSHRKDM4EHSD17B10ALDH1A1MAPT | |
| SCHEMBL4278364 | 0.85 | TSHR (0.44) | TSHRKDM4EHSD17B10ALDH1A1MAPT | |
| SCHEMBL4284397 | 0.85 | TSHR (0.44) | TSHRKDM4EHSD17B10ALDH1A1MAPT | |
| SCHEMBL28238622 | 0.85 | KDM4E (0.43) | TSHRKDM4EHSD17B10ALDH1A1MAPT | |
| SCHEMBL15521510 | 0.83 | DHODH (0.37) | TSHRKDM4EHSD17B10ALDH1A1MAPT | |
| SCHEMBL4273722 | 0.83 | ADRA1D (0.39) | TSHRKDM4EHSD17B10ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181205-B2 | Method for producing oxazole compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2015-11-10 | — | — | US | disclosed |
| US-20150239855-A1 | Method for Producing Oxazole Compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239855-A1 | Method for Producing Oxazole Compound | OXA1L, CYB5R3, CBR3 | TSHR 1502/4885KDM4E 1373/4885HSD17B10 879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.